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Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: Modeling of mitochondrial bioenergetics and autophagy impairment in MELAS-mutant iPSC-derived retinal pigment epithelial cells

Fig. 8

Alterations in mitochondrial bioenergetics in MELAS iPSC-RPE cells. A Schematic for the Seahorse XF Cell Mito Stress Test. B Mitochondrial oxygen consumption rate (OCR) in control iPSC-RPE, MELAS iPSC-RPE-hetlow, and MELAS iPSC-RPE-hethigh. C Changes in basal and spare respiratory capacities. D Changes in OCR. E Energy map showing changes in OCR and ECAR

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Stem Cell Research & Therapy

ISSN: 1757-6512