Fig. 1

Mice administrated by ADSC, Rg1, or ADSC + Rg1 are more tolerance to DSS-induced colitis. a Scheme of the animal experimental design. Mice were assigned to five groups randomly (control groups; DSS groups; Rg1 groups; ADSC groups; and ADSC + Rg1 groups). Mice were administered 3% DSS for 7 days followed by normal drinking water. At day 4 and 7 of DSS treatment, mice in ADSC and ADSC + Rg1 groups were intravenously injected with ADSC. Mice in Rg1 and ADSC + Rg1 groups were administered with Rg1 daily by oral gavage. On day 15, mice were killed. b Body weight change and final survival at day 15. n = 10–15. c Image displays the gross colon appearance. d Colon length was determined during necropsy. n = 10–15. e Representative H&E stained colon cross sections of mice at day 15 of the acute DSS colitis protocol. Bars, 200 μm. f H&E inflammatory score of colon sections. n = 6, * P < 0.05, **P < 0.01, ns, not significant