Table 2 List of observed adverse events. Observed adverse events were not serious, and the required medical considerations were applied in case they needed

Investigations

1

10001551

Alanine aminotransferase (ALT) increased

1

1

P-11/M6

2

10001675

Alkaline phosphatase (ALP) increased

1

4

P-3/M6

P-8/M6, 12

P-9/M12

5

P-2/M6, 9, 12

P-6/M6

P-10/M6

3

10003481

Aspartate aminotransferase (AST) increased

1

2

P-9/M12

P-11/M6

4

10025258

Lymphocyte count increased

2

1

P-2/M12

5

10047900

Weight loss

1

1

P-18/M6

General disorders and administration site conditions

6

10016558

Fever

1

1

P-18/M1

7

10022095

Injection site reaction

1

1

P-3/M1

1

P-6/W1

2

1

P-5/M1

1

P-6/M1

8

10033371

Pain (epigastric region)

1

1

P-12/M3

1

P-13/M2

Metabolism and nutrition disorders

9

10020587

Hypercalcemia

1

1

P-7/M12

10

10020647

Hyperkalemia

4

1

P-4/M12

11

10020907

Hyperuricemia

1

1

P-18/M12

12

10020949

Hypocalcemia

2

1

P-12/M12

14

10021018

Hypokalemia

1

1

P-14/M6

15

10021038

Hyponatremia

1

2

P-3/M12

P-9/M12

Skin and subcutaneous tissue disorder

16

10046735

Urticaria

3

1

P-1/First Injection

Endocrine

17

10021114

Hypothyroidism

1

1

P-8/M9

Neurology

18

10037175

Psychiatric disorders

1

1

P-8/M6