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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: FG-4592 protects the intestine from irradiation-induced injury by targeting the TLR4 signaling pathway

Fig. 1

FG-4592 exhibited a significant radioprotective effect in vivo and in vitro. A The survival of mice after total body irradiation of 8.5 Gy. B The survival of mice after local abdominal irradiation of 25.0 Gy. C Effects of different concentrations of FG-4592 on MODE-K cell viability was measured by the CCK-8 assay. D HIEC cell apoptosis was detected by flow cytometry. E Expression of HIEC cell apoptosis pathway-related proteins. The data were presented as mean ± SD. *P < 0.05, **P < 0.01, and ***P < 0.001 for control versus FG-4592 treatment

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