Fig. 2

FG-4592 protected the intestinal tissue against radiation-induced injury. C57BL/6 mice were pre-treated with PBS or FG-4592 before 8.5 Gy TBI. A Representative images of HE-stained intestinal sections with the indicated treatment at 3.5 d after TBI. B The representative images of Ki67-stained intestinal sections with the indicated treatment at 3.5 d after TBI. C The representative images of TUNEL-stained intestinal sections with the indicated treatment at 3.5 d after TBI. D The representative images of Lgr5⁺ FISH intestinal sections with the indicated treatment at 3.5 d after TBI. The data were presented as mean ± SD. *P < 0.05, **P < 0.01 and ***P < 0.001 for control versus FG-4592 treatment