Skip to main content

Table 1 Themes addressed in the included articles

From: Organoids: a systematic review of ethical issues

Author

Journal

Country

Year

Informed consent

Commercialization

Personalized drug testing

Transplantation

Brain organoids

Chimeras

Gastruloids

Aach et al.

eLif2

UK

2017

    

x

x

xx

Ankeny et al.

The American journal of bioethics

Australia

2020

    

xx

  

Bayne et al.

Trends in neuroscience

Australia/UK/Italy/Canada

2020

    

xx

  

Birch et al.

The American journal of bioethics

UK

2020

    

xx

  

Bitar et al.

Frontiers in molecular neuroscience

Australia

2020

    

x

x

 

Blue et al.

Neurosurgery

USA

2020

x

x

  

x

x

 

Boers et al.

EMBO rep

The Netherlands

2016

xx

xx

xx

xx

   

Boers et al.

Nature Cell Biology

The Netherlands

2018

xx

xx

  

x

x

 

Boers et al.

Journal of cystic fibrosis

The Netherlands

2018

xx

xx

xx

    

Boers et al.

Journal of medical ethics

The Netherlands

2019

xx

xx

xx

xx

x

x

x

Brazzanella

BioLaw journal

Italy

2021

    

x

  

Bredenoord et al.

Science

The Netherlands

2017

xx

xx

xx

xx

x

 

x

Buchanan

Nature Physics

USA

2018

    

x

x

 

Chen et al.

Developmental dynamics

USA

2019

x

 

x

x

x

x

 

Chen et al.

Cell stem cell

USA

2019

x

   

x

xx

 

Chhibber et al.

Drug discovery today

USA

2020

x

x

  

x

x

 

Choudhury et al.

Trends in molecular medicine

Singapore

2020

x

x

   

x

 

Cleber et al.

Trends mol med,

USA

2018

    

x

  

Denker

Cells

Germany

2021

      

xx

Farahany

Nature

USA

2018

x

x

  

xx

xx

 

Felsen et al.

The journal of law, medicine and ethics

USA

2019

    

xx

  

Greely

The American Journal of bioethics

USA

2020

x

   

xx

xx

 

Haselager et al.

Regenerative medicine

The Netherlands

2020

xx

x

xx

 

xx

  

Hostiuc et al.

Regenerative therapy

Romania

2019

    

xx

xx

x

Hyun et al.

Brain research

USA

2020

xx

x

xx

x

xx

xx

 

Hyun et al.

Cell stem all

USA

2017

x

x

x

 

x

  

Kamm et al.

APL Bioengineering

USA

2018

    

x

 

x

Koplin et al.

Journal of medical ethics

Australia

2020

x

   

xx

xx

 

Koplin et al.

Journal of law, medicine and ethics

Australia

2019

x

   

xx

x

 

Koplin et al.

Monash Bioethics Review

Australia

2020

    

xx

xx

 

Lavazza

Journal medical ethics

Italy

2019

xx

xx

  

x

x

 

Lavazza

Brain research

Italy

2020

    

xx

 

xx

Lavazza et al.

Journal of law and the Bioscience

Italy

2020

    

xx

x

 

Lavazza et al.

Neuroethics

Italy

2018

 

x

  

xx

x

 

Lavazza et al.

Medical journal of medical ethics

Italy

2018

x

x

  

xx

  

Lavazza

Monash Bioethics review

Italy

2020

    

xx

xx

 

Lensink et al.

Development

The Netherlands

2020

xx

xx

x

 

x

x

x

Lensink et al.

Personalized medicine

The Netherlands

2020

xx

xx

xx

    

Lensink et al.

Journal of cystic fibrosis

The Netherlands

2020

xx

xx

xx

    

Li et al.

Biopreservation and biobanking,

China

2020

x

x

  

x

  

Lunshof

The American journal of bioethics

The Netherlands

2020

    

xx

  

Lyon et al.

Brain

UK

2019

    

x

  

Munsie et al.

Development

Australia

2017

xx

x

  

x

xx

xx

Munsie et al.

Genetics and development

Australia

2018

x

x

  

x

xx

x

Ooi et al.

The neuroscience

Australia

2020

x

   

x

  

Pera et al.

Nature methods

Australia

2015

      

xx

Pereira Daoud et al.

Human reproductive update

The Netherlands

2020

      

xx

Reardon

Nature

 

2018

    

x

  

Reardon

Nature

USA

2020

    

xx

  

Rinaldi

Future medical chemistry

Italy

2018

x

 

x

x

x

  

Rivron and Pera et al.

Nature

The Netherlands/USA

2018

      

x

Sample

Biofabrication

Canada/USA

2019

 

x

   

x

 

Sawai et al.

Stem cell reports

Japan

2019

    

xx

xx

 

Sawai et al.

AJOB neuroscience

Japan

2021

x

   

xx

xx

 

Schneeman et al.

Science translational medicine

The Netherlands

2020

   

xx

   

Sharma and Zuk et al.

The American journal of bioethics

USA

2020

    

xx

  

Shepherd et al.

Journal of medical ethics

Canada

2018

    

xx

  

Sugarman and Bredenoord

Science and society EMBO reports

USA/The Netherlands

2020

x

x

 

x

 

x

x

Sugarman and Bredenoord

Cell stem cell

USA/The Netherlands

2019

xx

xx

xx

xx

xx

xx

xx

Wei et al.

Reproductive science

China

2021

x

    

x

x

Xinaris et al.

Current opinion organ transplant

Italy

2019

    

x

  

Zuradzki

The American journal of bioethics

Poland

2020

    

x

  

Total

   

31

23

13

9

49

30

16

  1. x: Mentions the theme as an ethical issue
  2. xx: Ethical issue is elaborately discussed in the paper