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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Oncostatin M receptor regulates osteoblast differentiation via extracellular signal-regulated kinase/autophagy signaling

Fig. 6

OSMR silencing relieved the bone loss phenotype in OVX mice. Representative images of H&E staining are shown. Scale bar, upper panel: 500 μm; lower panel: 100 μm (A). The number (B) and area (C) of adipocytes were quantified. Representative images of ALP immunohistochemical staining are shown. Scale bar: 25 μm (D). The number of osteoblasts on the trabeculae was quantified (E). μCT analysis of bone mass in the proximal metaphysis of tibiae was done and the reconstruction images are shown (F). Histomorphometric parameters were analyzed in the mice (GJ). Values are mean ± SD. AE, n = 5; GJ, n = 8. *p < 0.05 vs. Sham/Ctrl LV. #p < 0.05 vs. OVX/Ctrl LV

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