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Table 1 Patient characteristics of MSC group and non-MSC group

From: Mesenchymal stromal cell treatment improves outcomes in children with pneumonia post-hematopoietic stem cell transplantation: a retrospective cohort study

 

MSC group (n = 47)

Non-MSC group (n = 60)

p value

No. (%)

No. (%)

Age (year)

Mean ± SD (range)

6.19 ± 3.04 (1.10–15)

6.54 ± 2.94 (1.10–15)

0.608

 ≤ 7

33 (70.21)

42 (70.00)

0.981

 > 7

14 (29.79)

18 (30.00)

 

Sex

0.778

 Male

31 (65.96)

38 (63.33)

 

 Female

16 (34.04)

22 (36.67)

 

Pneumonia

0.306

 Non-severe

31 (65.96)

45 (75)

 

 Severe

16 (34.04)

15 (25)

 

HSC sourcea

0.454

 Peripheral blood

41 (87.23)

55 (91.67)

 

 Umbilical cord blood

6 (12.77)

5 (8.33)

 

HSC donor typeb

0.800

 Matched

27 (57.45)

33(55.00)

 

 Mismatched

20 (42.55)

27 (45.00)

 

Primary diseases

0.176

 Thalassemia

36 (76.60)

52 (86.67)

 

 Others

11 (23.40)

8(13.33)

 

Interval daysc

 ≥ 100

20 (42.55)

19 (31.67)

0.246

 < 100

27 (57.45)

41 (68.33)

 

Virus serostatus

0.725

 Negative

29 (61.70)

39 (65.00)

 

 Positive

18 (38.30)

21 (35.00)

 

Virus (serostatus + BAL)d

 Negative

23 (48.94)

33 (55.00)

0.533

 Positive

24 (51.06)

27 (45.00)

 

Bacteria/fungi

0.454

 Negative

41 (87.23)

55 (91.67)

 

 Positive

6 (12.77)

5 (8.33)

 

MSC infusion times

 Mean ± SD (Median, range)

4.04 ± 2.11 (4, 1–11)

  
  1. a,bHSC: hematopoietic stem cell
  2. cDays between pneumonia onset and hematopoietic stem cell transplantation
  3. dBAL: bronchoalveolar lavage fluid