Skip to main content
Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: TSG-6 released from adipose stem cells-derived small extracellular vesicle protects against spinal cord ischemia reperfusion injury by inhibiting endoplasmic reticulum stress

Fig. 7

ADSC-sEVs transported TSG-6 proteins into spinal cord tissue and overexpression of TSG-6 enhanced the capacity of sEVs to improve motor function after SCIRI. a. Expression of TSG-6 expression in spinal cord tissue after ADSC-sEVs administration as determined by Western blotting analysis. b Relative expression levels of TSG-6 in spinal cord tissues, normalized to GAPDH. c Expression of TSG-6 in ADSC-sEVs as determined by Western blotting assay. d, e Determination of TSG-6 expression in Lenti-TSG-6-sEVs and Lenti-Ctrl-sEVs by Western blotting assay. f, g Values of Basso Mouse Scale (BMS) and inclined plane test at different times after SCIRI. h Representative images of the footprint assay performed 28 days after SCIRI. *p < 0.05 compared with the SCIRI group, #p < 0.05 compared with the Lenti-Ctrl-sEVs group

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512