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Fig. 9 | Stem Cell Research & Therapy

Fig. 9

From: TSG-6 released from adipose stem cells-derived small extracellular vesicle protects against spinal cord ischemia reperfusion injury by inhibiting endoplasmic reticulum stress

Fig. 9

Overexpression of TSG-6 suppressed ER stress by modulating the PI3K/AKT signaling pathway. a Representative images of GRP78-positive neurons in each experimental group. b Quantitative analysis of GRP78-positive neurons. c Expression of ER stress-related proteins as determined by Western blotting analysis. d, e Relative expression levels of ER stress-related proteins normalized to GAPDH. f Western blot analysis of AKT protein. g Relative expression levels of p-AKT normalized to GAPDH. *p < 0.05 compared with the SCIRI group, #p < 0.05 compared with the Lenti-Ctrl-sEVs group

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