Fig. 6

In vivo lineage potential of hESC-derived CD45⁺ cells. A and B Human CD45⁺ cells were measured by flow cytometry in peripheral blood of the mice transplanted with CB CD34⁺ cells and hESC-derived CD45⁺ cells at one month post-transplantation. C and D Myeloid lineage C and lymphoid lineage D contribution by CB CD34⁺ cells and hESC-derived CD45⁺ cells in peripheral blood of engrafted mice at one month post-transplantation. Flow analysis for myeloid cells (CD11b), granulocyte cells (CD16), B cells (CD19), NK (CD56) and T cells (CD3) within the human CD45⁺ population. E and F Human CD45⁺ cells were measured by flow cytometry in bone marrow in the mice transplanted with CB CD34⁺ cells and hESC-derived CD45⁺ cells at one month post-transplantation. G and H Myeloid lineage E and lymphoid lineage H contribution by CB CD34⁺ cells and hESC-derived CD45⁺ cells in bone marrow of engrafted mice at one month post-transplantation. Flow analysis for myeloid cells (CD11b), granulocyte cells (CD16), B cells (CD19), NK (CD56) and T cells (CD3) within the human CD45⁺ population. Data represent the mean ± SEM. *p < 0.05