Fig. 4

Ad5-Ki67/IL-15 reduced angiogenic capacity of MSCs. A–C Tube formation capacity of GA-MSCs cultured with viruses. The viruses inhibited the formation of vascular-like structures by GA-MSCs. D–F Angiogenic capacity of GA-MSCs incubated in conditioned media from GL261 treated with viruses. Conditioned media from U251 cells treated with viruses decreased GA-MSC angiogenesis (× 50, scale bars = 2000 µm). All MOI = 40. *P < 0.05, **P < 0.01