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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Tongxinluo-pretreated mesenchymal stem cells facilitate cardiac repair via exosomal transfer of miR-146a-5p targeting IRAK1/NF-κB p65 pathway

Fig. 3

Characterization of exosomes derived from MSCs. A MSCs-exo and MSCsTXL-exo were assessed by TEM and exhibited cup-shaped morphology. Scale bar = 200 μm. B NTA was performed to characterize the particle size and concentration. C Representative western blotting images of exosomal protein markers and MSCs markers. D Representative confocal images indicated that PKH26 labeled exosomes were taken up by H9C2 cells after 12 or 24 h of incubation. Scale bar = 20 μm. E PKH26-labeled MSCs-exo could be taken up by cardiomyocytes in infarcted hearts on Day 3 post-AMI. Scale bar = 50 μm

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