Fig. 4
Exosomes derived from MSCsTXL protected H9C2 cells against apoptosis. Representative images of the flow cytometry assay (A) and quantification (B) of apoptosis of H9C2 cells after pretreatment with different concentrations of MSCs-exo (n = 5). Representative images of flow cytometry (C) and quantification (D) of apoptosis of H9C2 cells pretreated with 10 μg/mL MSCs-exo or MSCsTXL-exo under H/SD conditions (n = 5). Representative images of western blotting (E) and quantification of Bax (F) and cleaved-Caspase 3 (G) levels after exosome pretreatment (n = 4). Data were analyzed with one-way ANOVA followed by Tukey’s test and are presented as the mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001