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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Amphiregulin regulates odontogenic differentiation of dental pulp stem cells by activation of mitogen-activated protein kinase and the phosphatidylinositol 3-kinase signaling pathways

Fig. 4

The effect of AREG on the regeneration and mineralization of hDPSCs in vivo. A Micro-CT images of the DPSC/S-scaffold construct in nude mice after subcutaneous implantation for 4 weeks. A (a) and (b) show the DPSC/NF-gelatin-scaffold composites of the control and AREG group, respectively. B Quantitative analysis of micro-CT images (a) BV/TV (Bone Volume to Tissue Volume); (b) Tb.Th. (Trabecular Thickness); (c) Tb.N. (Trabecular Number); (d) Tb.Sp. (Trabecular Separation). C Histological staining of the DPSC/S-scaffold construct after subcutaneous implantation in nude mice for 4 weeks. (a, d, g) H&E staining; (b, e, h) Masson staining; (c, f, i) Von Kossa staining. *P < 0.05 represents a significant change compared with the control

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