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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Comparison of therapeutic effects of mesenchymal stem cells from umbilical cord and bone marrow in the treatment of type 1 diabetes

Fig. 4

Effects of BM-MSCs or UC-MSCs infusion on insulitis in NOD mice. A Representative micrographs of H&E staining of pancreas at 14 days post-transplantation. Scale bar, 100 μm. B The percentage of islets in each of the infiltration categories (score 0, no insulitis; score 1, leukocyte infiltration ≤ 25%; score 2, leukocyte infiltration > 25%, but ≤ 50%; score 3, leukocyte infiltration > 50%; score 4, leukocyte infiltration 100% and β-cell destruction). C Insulitis score in pancreatic islets. Four slides per mouse (four mice per group) were analysed, and at least 20 islets from the pancreatic tissue of each mouse were evaluated. Data are presented as mean ± SEM. *P < 0.05 versus the control group

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