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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: CCL20/CCR6 axis mediates macrophages to promote proliferation and migration of ESCs by blocking autophagic flux in endometriosis

Fig. 7

Blocking CCL20/CCR6 axis suppresses the progression EMs in vivo. A Cartoon illustration of animal experiments protocol (created in BioRender.com). n = 6 mice in each group per time point. B HE staining of mice uterus and ectopic lesions from CCL20-NAb-treated group and control group. (original magnification 200 ×) C Data for body weight of mice in different groups at different time points. D Representative images of ectopic lesions in CCL20-NAb-treated group and control group mice at day 5, day 9, day 14. Black arrowheads point to ectopic lesions. E Macrograph of representative ectopic lesions in two groups at day 5, day 9, day 14. F Data for lesion weight of two groups mice at day 5, day 9, day 14. G Data for lesion volume of two groups mice at day 5, day 9, day 14. H The protein level of CCR6, LC3, P62 and Ki67 in ectopic lesions from two groups by western blot. I Quantification of the gray value of CCR6, LC3, P62 and Ki67 western blot bands in ectopic lesions from two groups. Data are presented as mean ± SD. Statistical analysis was performed using Mann–Whitney test (C, F, G, I). ***p < 0.001, *p < 0.05, ns, non-significant

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