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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: IL-37 overexpression promotes endometrial regenerative cell-mediated inhibition of cardiac allograft rejection

Fig. 5

IL-37-ERCs reduced recipients' splenic Th1 and Th17 populations while increasing the generation of Tregs. Splenocytes obtained from the C57BL/6 recipients of each group were stained with CD4+IFN-γ+IL-17A+ and CD4+CD25+Foxp3+, respectively. The representative pseudocolor plots of Th1 cells (A), Th17 cells (B), and Tregs (C) were exhibited. The percentage of D Th1 cells, E Th17 cells, and F Tregs (CD4+CD25+Foxp3+) were analyzed by one-way ANOVA, n = 6 per group, *P < 0.05, **P < 0.01, ***P < 0.001, ns = non-significant. For all panels, the bar graphs represent mean ± SD

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Stem Cell Research & Therapy

ISSN: 1757-6512