Fig. 2

Identification of the 4-key-genes correlated with ICC prognosis. A Heatmap of the key genes in orange module. B Kaplan–Meier curve of the overall survival of ICC patients in correlation with 4-key-genes expression in TCGA database. C The mRNA expression of 4-key-genes in multiple cancer types from Oncomine database. The number in the colored cell represents the number of analyses meeting these thresholds. The red cells indicate that the genes are higher in tumor tissues than in normal tissues, while blue cells indicate an opposite expression pattern. D Correlation between key genes at the transcriptional level