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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: A gene signature is critical for intrahepatic cholangiocarcinoma stem cell self-renewal and chemotherapeutic response

Fig. 3

4-key-genes are associated with stemness maintenance of cholangiocarcinoma CSCs. A and B Pluripotent transcription factors were analyzed in SDHAF2 (and MRPS34) depletion or overexpression cells by qRT-PCR (A) and western blot (B). C SDHAF2 or MRPS34 overexpression caused an enhanced oncosphere-forming capacity in RBE cells; the right panel represents statistical results as means ± SD; Scale bar, 100 μm. D The transcriptional level of 4-key-genes in 40 ICC tissues. (*p < 0.05, **p < 0.01, ***p < 0.001)

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Stem Cell Research & Therapy

ISSN: 1757-6512