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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Human umbilical cord blood-derived MSCs trans-differentiate into endometrial cells and regulate Th17/Treg balance through NF-κB signaling in rabbit intrauterine adhesions endometrium

Fig. 6

RNA sequencing and bioinformatics analysis reveal biological pathways involved in IUA treated with hUCB-MSCs. A The volcano plot of differential expressed genes in IUA before and after hUCB-MSCs transplantation. Red (or blue) color indicates up-regulated (or down-regulated) genes. B The heatmap of representative differential expressed genes. C The enriched GO terms in GO enrichment analysis. D The enriched KEGG pathways in pathway enrichment analysis. E The NFKB1 mRNA expression (FPKM) measured by RNA sequencing in two groups, each group has three samples. F The NFKB1 mRNA expression level detected by qRT-PCR assay in 5 groups, each group has three samples. G The representative WB image of NF-κB p65 protein expression. H The NF-κB p65 protein expression level measured by WB in 5 groups, i.e., rabbits without surgery (control), 14/28th day after surgery, and treated with estrogen/hUCB-MSCs

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Stem Cell Research & Therapy

ISSN: 1757-6512