Skip to main content
Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Organ-specific extracellular matrix directs trans-differentiation of mesenchymal stem cells and formation of salivary gland-like organoids in vivo

Fig. 5

Ultrastructural characteristics of rat SMG tissue and SMG-ECM-treated aggregates were remarkably similar. A Transmission electron micrographs of rat SMG (positive control tissue) thin sections. N: cell nucleus; SG: secretory granule (note: there are two types: electron dense and less electron dense); TJ: tight junction. B Transmission electron micrographs of SMG-ECM-treated cell aggregates formed during 14 days in culture. Note the presence of structures (e.g., electron dense and less electron dense secretory granules; formation of tight junctions; and location of nucleus near the cell membrane) found in the rat SMG tissue that can also be seen in the cell aggregates. C Transmission electron micrographs of monolayer (Mono/SMG-ECM) and untreated BM-MSCs. Note: scale bar distances are shown in each panel

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512