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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Exosomal miR-132-3p from mesenchymal stromal cells improves synaptic dysfunction and cognitive decline in vascular dementia

Fig. 3

EXmiR-132-3p infusion rescues synaptic deficits in VD mice. A Representative Golgi staining from cortex and hippocampus regions are shown. Scale bar, 10 μm. B The effects of MSC EX injection on cortical dendritic arborization in Sham and VD mice. CE Representative images and summary data of dendritic spines from cortical and hippocampal neurons from VD mice after treated with EXCon/EXmiR-132-3p/EXantagomiR-132-3p. Data represent the mean ± SEM. n = 20 neurons from 3 mice per group. Three independent experiments were performed. *p < 0.05

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