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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Exosomal miR-132-3p from mesenchymal stromal cells improves synaptic dysfunction and cognitive decline in vascular dementia

Fig. 4

EXmiR-132-3p infusion reduces cortical neuron loss and abnormal architecture in hippocampal CA1 region in VD mice, injected with various MSC EX. A, C The cortical neuron number in Sham and VD mice was detected by immunofluorescence staining (NeuN, green; DAPI, blue). B, D Representative images and summary data showing the hippocampal neuron number and architecture in VD mice by immunochemistry. Data represent the mean ± SEM. n = 20 fields from 3 mice per group. Three independent experiments were performed. *p < 0.05

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