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Fig. 9 | Stem Cell Research & Therapy

Fig. 9

From: A defined road to tracheal reconstruction: laser structuring and cell support for rapid clinic translation

Fig. 9

Histological analysis of implanted decellularized matrices and cartilage constructs (highlighted with dotted line) in rabbits, major magnification, hematoxylin–eosin, scale bar—100 µm. Peri-implant capsule consisted of blood vessels, fibroblasts, leukocytes (prevailing at weeks 4 and 8) and foreign body cells (prevailing at weeks 12 and 16). The submucosal component was resorbed in both groups by week 12. Cartilaginous component microstructure of the tissue-engineered constructs was changed by week 16 due to multiple invading immune cells leading to fractures in the implant macrostructure

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