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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Embryonic stem cell-derived mesenchymal stem cells alleviate skeletal muscle injury induced by acute compartment syndrome

Fig. 6

Effect of ESC-MSCs on skeletal muscle fibrosis, regeneration, and functional recovery 7 days after ACS. a Representative image of fibrosis in each group, as shown by Masson trichrome staining. b Representative images of muscle regeneration, as shown by H&E staining. Regenerating myofibers were defined by myofibers containing a central nucleus (original magnification, ×200). c Quantitative analysis of the fibrotic area in each group. d and e Quantitative analysis of the number (d) and diameter (e) of regenerating myofibers in each group. f and g The grip strength (f) and hanging time (g) in each group. N = 7. The data are presented as the mean ± SD, and there were no significant among the sham groups. *P < 0.05 versus sham treated with PBS and #P < 0.05 versus ACS treated with PBS

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