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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Embryonic stem cell-derived mesenchymal stem cells alleviate skeletal muscle injury induced by acute compartment syndrome

Fig. 7

Effects of ESC-MSCs on macrophage polarization and the mRNA expression of inflammatory factors in skeletal muscle after ACS. a The distribution of labeled ESC-MSCs in the lung and skeletal muscle tissue of rats at various time points. b Representative western blotting images. c Quantitative analysis of CD68 expression. d Quantitative analysis of CD86 expression. e Quantitative analysis of CD206 expression. f Quantitative analysis of CD206/CD86 ratio. g Representative images of M1-polarized macrophage (CD86) and M2-polarized macrophage (CD206) infiltration in skeletal muscle after PBS or ESC-MSC infusion. h Quantitative real-time PCR data showing the mRNA levels of TNF-α, IL-6, and IL-10 in skeletal muscle after PBS or ESC-MSC infusion. N = 7. The data are presented as the mean ± SD. *P < 0.05 versus ACS treated with PBS

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Stem Cell Research & Therapy

ISSN: 1757-6512