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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: miR-126-3p-loaded small extracellular vesicles secreted by urine-derived stem cells released from a phototriggered imine crosslink hydrogel could enhance vaginal epithelization after vaginoplasty

Fig. 4

piGEL-sEVs promoted vaginal epithelium regeneration and angiogenesis. A IF staining for AE1/AE3 at days 7 and 14 after the operation. Scale bar: 50 μm. B Quantitative analysis of IF staining of AE1/AE3. n = 3 per group. C IF staining for CD31 at day 7 after the operation. Scale bar: 50 μm. D Quantitative analysis of new vessel number. n = 3 per group. E IF staining for α-SMA at day 14 after the operation. Scale bar: 50 μm. F Quantitative analysis of IF staining of α-SMA. n = 3 per group. *, P < 0.05, compared with the PBS group; #, P < 0.05, compared with the piGEL group; %, P < 0.05, compared with the sEVs group

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