Fig. 1From: Extracellular vesicles derived from human umbilical cord mesenchymal stem cells alleviate osteoarthritis of the knee in mice model by interacting with METTL3 to reduce m6A of NLRP3 in macrophageIdentification of human umbilical cord MSCs and EVs. A. A typical spindle-like morphology of hucMSCs. B. Flow cytometry analysis showed that hucMSCs expressed specific markers on their surface. C. Transmission electron microscope image of hucMSCs-EVs. D. Particle size distribution of hucMSCs-EVs analyzed by NanoSight. E. EVs special markers (CD9, CD63, Alix, TSG101) analyzed by western blot. F. Macrophages endocytose EVs observed by fluorescence microscopeBack to article page