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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Extracellular vesicles derived from human umbilical cord mesenchymal stem cells alleviate osteoarthritis of the knee in mice model by interacting with METTL3 to reduce m6A of NLRP3 in macrophage

Fig. 1

Identification of human umbilical cord MSCs and EVs. A. A typical spindle-like morphology of hucMSCs. B. Flow cytometry analysis showed that hucMSCs expressed specific markers on their surface. C. Transmission electron microscope image of hucMSCs-EVs. D. Particle size distribution of hucMSCs-EVs analyzed by NanoSight. E. EVs special markers (CD9, CD63, Alix, TSG101) analyzed by western blot. F. Macrophages endocytose EVs observed by fluorescence microscope

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