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Fig. 10 | Stem Cell Research & Therapy

Fig. 10

From: Mesenchymal stem cell-derived exosomes protect against liver fibrosis via delivering miR-148a to target KLF6/STAT3 pathway in macrophages

Fig. 10

MiR-148a agomir infusion attenuated liver fibrosis in mice. A The level of miR-148a in liver was detected by RT-PCR assay. B Reparative histological images of PBS, NC-agomir and miR-148a agomir infusion by HE, Sirius red staining and Masson staining, two weeks after injection. C Quantification of fibrotic area (Sirius red and Masson). D Representative images showed the Col1a1 + and αSMA + cells in each group. The nuclei were stained with DAPI. Quantification of Col1a1 + and αSMA + areas was calculated by Image-Pro Plus. E, F The protein level of Col1a1, αSMA and quantification of Col1a1, αSMA bands related to actin was calculated by Image-Pro Plus

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Stem Cell Research & Therapy

ISSN: 1757-6512