Fig. 2

CEFFE improved the fertility of POI mice. A Representative images of 2-cell embryo, 4–8-cell embryo, morular and blastocyst from the different groups. B Typical images of progeny in each group. C Statistical analysis of oocytes retrieved in each group (n = 6). D Statistical analysis of the 2-cell embryo ratios (2-cell embryo/total oocytes retrieved) in each group (n = 6). E Statistical analysis of blastocyst ratios (blastocyst/2-cell embryo) in each group (n = 6). F Statistical analysis of litter size in each group (n = 5–8). All data are represented as the mean ± SD. ns: P > 0.05, *P < 0.05, **P < 0.01, ***P < 0.001, compared with POI group