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Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: Oxidative stress-induced endothelial cells-derived exosomes accelerate skin flap survival through Lnc NEAT1-mediated promotion of endothelial progenitor cell function

Fig. 8

H2O2-HUVEC-Exos increased neovascularization of flaps and recruitment of EPCs. A H&E staining of three groups of skin flaps. B The representative immunohistochemistry staining of CD31 and α-SMA in control, HUVEC-Exos, si-NEAT1-HUVEC-Exos, H2O2-HUVEC-Exos, si-NEAT1-H2O2-HUVEC-Exos groups. C. Quantitative analysis of CD31 and α-SMA positive vessel number. D Quantitative analysis of the number of CD34/CD133 double positive cells. E The representative immunofluroscence staining of CD133 and CD34 positive cells. CD133 positive cells were shown in red. CD34 positive cells were shown in green. ns. P > 0.05, * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001 vs. control group

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