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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Mesenchymal stem cells derived from adipose accelerate the progression of colon cancer by inducing a MT-CAFs phenotype via TRPC3/NF-KB axis

Fig. 5

TRPC3 regulates the proliferation of MT-MSCs in vitro. A MTS assay in MT-CAFs with different treatments including control MSCs, MSCs with 100 ng or 200 ng of stimulus, MSCs with OAG (TRPC3 agonist), MSCs with pyr3 (TRPC3 inhibitor 1 µM or 2 µM). The data represent the means ± S.D. (*P < 0.05; **P < 0.01 by Student’s t-test). B Clone formation assay in MT-CAFs with six different treatments. C Quantitative results (P < 0.05). D MTS assay in HCT116 cells following different treatments. E Clone formation assay in HCT116 cells with four different treatments. F Statistical analysis of the results shown in figure E (P < 0.05)

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Stem Cell Research & Therapy

ISSN: 1757-6512