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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Mesenchymal stem cells derived from adipose accelerate the progression of colon cancer by inducing a MT-CAFs phenotype via TRPC3/NF-KB axis

Fig. 6

H-exos regulate the function of MT-CAFs via the TRPC3/NF-κB signaling pathway. A, B Analysis of gene expression profiles indicated that various signaling pathways were activated in MT-CAFs following stimulation with H-exos. C WB confirmed that the relevant signaling pathways were activated in MT-CAFs compared to the MSCs. D Activation of NF-κB was positively correlated with TRPC3 in MT-CAFs according to western blot analysis. E The phosphorylation of NF-κB protein were detected by immunofluorescence staining

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