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Table 1 Cell transplantation in diabetic mellitus model dogs

From: Reprogramming adipose mesenchymal stem cells into islet β-cells for the treatment of canine diabetes mellitus

Group

Cells

Graft site

aMSCs + ra-βCs (n = 4)

5 × 106 ra-βCs/kg + 5 × 106.aMSCs/kg

Remaining pancreatic tissue

aMSCs + ra-βCs (Testicle) (n = 4)

5 × 106 ra-βCs/kg + 5 × 106.aMSCs/kg

Testicle

aMSCs (n = 4)

5 × 106.aMSCs/kg

Remaining pancreatic tissue

ra-βCs (n = 4)

5 × 106 ra-βCs/kg

Remaining pancreatic tissue

PBS (n = 3)

PBS

Remaining pancreatic tissue

PBS + Insulin (n = 3)

PBS

Remaining pancreatic tissue, and daily subcutaneous injection of norphin N medium-effect insulin