Fig. 3

Heatmap of matured metabolism in iPSC-CMs. Overview of the fold changes (after logarithmic transformation) in different metabolic categories to visualize the highest metabolic maturation in iPSC-CMs. A Respiration, B ATP production, C FA metabolism, D mitochondria, E glucose metabolism, F lactate metabolism. The y-axis depicts the different studies indicated by the first author and multiple studies by the same author are indicated by (year) behind the name. Some studies included multiple conditions that were measured separately, indicated by dashes directly under the author name. The x-axis depicts the subcategories within each category. The values that are reported as changed in maturation are indicated by ( +), values that are expected to decrease are indicated by ( −). Studies that did not include measurements in the respective categories were not included in this overview