Fig. 5

Traumatic impact-induced changes in matrix deposition and catabolic enzyme production. Rows: Engineered cartilage constructs were subjected to 30% strain or exposed to 10 ng/ml IL-1β at 1, 3 and 7 days of culture. Columns: samples were histochemically stained with hematoxylin and eosin or Safranin O/Fast Green or immunohistochemically processed to detect COL2, MMP13 or ADAM-TS4. magnification = 100 × (inset = 40 ×)