Fig. 3
From: Human fibroblasts facilitate the generation of iPSCs-derived mammary-like organoids
Mammary gland development-associated genes’ expression during MLOs formation. A The expression of genes in mammary gland morphogenesis and branching morphogenesis of epithelial tube increased gradually during MLOs generation; B The expression of genes involved in Wnt signaling pathway increased gradually during MLOs formation; C the expression of genes involved in cell division, cell cycle, regulation of transcription and telomere maintenance decreased gradually during MLOs generation. Statistical significance was determined using one-way ANOVA with a Tukey posttest correction. RT-qPCR have been repeated at least three times. Data are depicted as mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001