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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Neurotrophic factor-secreting cells restored endogenous hippocampal neurogenesis through the Wnt/β-catenin signaling pathway in AD model mice

Fig. 4

Immunofluorescence imaging for Dil-labeled NTF-SCs (A–D). Monitoring the potency of Dil-labeled NTF-SCs to express nestin marker one day after transplantation into the DG (A). Differentiation of Dil-labeled NTF-SCs into mature NeuN.+ neurons 35 days after cell transplantation (B). Assessment of the NTF-SCs in the SGZ niche suggested that 62.6% and 52.5% of the labeled cells were positive for double Dil/Nestin (C) and Dil/NeuN (D), respectively. One-way ANOVA and Tukey post hoc analysis. *p < 0.05; **p < 0.01; and ***p < 0.001

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Stem Cell Research & Therapy

ISSN: 1757-6512