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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: C/EBPα regulates the fate of bone marrow mesenchymal stem cells and steroid-induced avascular necrosis of the femoral head by targeting the PPARγ signalling pathway

Fig. 7

Curcumin rescues SANFH by inhibiting PPARγ expression in vivo. a Expression levels of PPARγ, ALP and Runx2 in the femoral heads of each group as detected by western blot. b 3D reconstructed images of the femoral head. c Circular region of interest (r = 0.75 mm) in images for evaluating internal bony structure and bone marrow cavity. d BMD analysis of femoral heads in each group. e, f H&E staining for assessing the levels of intramedullary fat in each group, with black arrows indicating fat vacuoles. g, h IHC analysis of PPARγ expression in each group. ***P < 0.001, **P < 0.01, *P < 0.05, ns = not significant

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