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Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: Melatonin in cryopreservation media improves transplantation efficiency of frozen–thawed spermatogonial stem cells into testes of azoospermic mice

Fig. 8

Hematoxylin and eosin staining of mouse testis after 2 months. Images show complete spermatogenesis in the control group, elimination of spermatogenesis in the busulfan group, and recovery of spermatogenesis after transplantation of frozen–thawed SSCs into the testes of azoospermic mice in freeze and freeze + Mel groups. The recovery of spermatogenesis was significant in the freeze + Mel group compared to freeze group. (a). Quantification of histological analyses indicates a significant increase in spermatogenesis recovery in freeze + Mel group compared to freeze group (b). Scale bar = 100 μm. The results are presented as mean ± SD. ***p < 0.001

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