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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Mesenchymal stem cells improve liver fibrosis and protect hepatocytes by promoting microRNA-148a-5p-mediated inhibition of Notch signaling pathway

Fig. 3

HUC-MSCs ameliorate BDL-induced liver fibrosis in mice. a Schema depicting HUC-MSCs treatment for BDL-induced liver fibrosis. b Representative images of liver gross morphology of sham, BDL, and BDL + MSC groups, and images of H&E, Masson, Sirius red, and α-SMA immunohistochemistry staining of liver sections of the three groups. Scale bars, 200 µm. c Kaplan–Meier survival analysis of mice in the three groups. d The amount of liver hydroxyproline was detected in the different groups. Each experiment was repeated three times. *P < 0.05, **P < 0.01, ***P < 0.001 and n.s. not significant. HUC-MSCs human umbilical cord mesenchymal stem cells; α-SMA α-smooth muscle actin

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