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Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: Ectoderm-derived frontal bone mesenchymal stem cells promote traumatic brain injury recovery by alleviating neuroinflammation and glutamate excitotoxicity partially via FGF1

Fig. 8

Proposed mechanism. FbMSC application reduces the activation of microglia cells and astrocytes and alleviates glutamate excitotoxicity. Abbreviations: FGF1, acidic fibroblast growth factor1; FGFR, acidic fibroblast growth factor1 receptor; GLT-1, glutamate transporter-1; GLAST, glutamate-aspartate transporter; iNOS, inducible nitric oxide synthase; IL6, interleukin 6; IL-10, interleukin-10

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Stem Cell Research & Therapy

ISSN: 1757-6512