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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Retinoic acid and FGF10 promote the differentiation of pluripotent stem cells into salivary gland placodes

Fig. 5

Generation of SG placodes from mESCs cell line F15. A–C Similar to 129w2 mESCs-derived SG placodes, the F15-derived SG placodes formed invaginating epithelium and initial bud-like structures from D6 to D10. Scale bars: 50 μm. D–E F15-derived SG placodes also showed polarized expression of Krt19 in developing ducts, but not in the invaginating epithelium. Scale bars: 25 μm (D) and 50 μm (E)

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Stem Cell Research & Therapy

ISSN: 1757-6512