Fig. 3

Ovarian functions after graft transplantation. A Histological analysis of biocompatibility between ovarian tissue and 3D scaffold with/without ADSCs. Scale bar: 500 µm and 200 µm. B Histological analysis of ovaries in six different groups. Scale bar: 200 µm and 100 µm. C Number of follicles at different stages counted at 1, 2, and 4 weeks after graft transplantation. D The levels of E2, FSH, and AMH were analyzed at 1, 2, and 4 weeks after graft transplantation. (* versus the normal group, # versus the POI group, & comparison between two groups; *, #, & P < 0.05; **, ##, && P < 0.01; ***, ###, &&& P < 0.001). E Changes of irregular estrous cycles