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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Podocytes derived from human induced pluripotent stem cells: characterization, comparison, and modeling of diabetic kidney disease

Fig. 5

Integration of iPSC-derived podocytes into mouse embryonic kidneys. A Brightfield images of the recombinant organoids generated using iPSC-podocytes and E12.5 embryonic kidney at day 2 and day 7 after initiation of ex vivo co-culture. B Higher (40x, i) and lower (20x, ii) magnification images showing the iPSC-derived podocytes (human-specific MAFB+, red) incorporated into mouse glomerular structures (mouse-specific NPHS1+, green) (n = 2). Counterstaining with DAPI (blue). Scale bar is 50 μm

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Stem Cell Research & Therapy

ISSN: 1757-6512