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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Integrin receptor-binding nanofibrous peptide hydrogel for combined mesenchymal stem cell therapy and nitric oxide delivery in renal ischemia/reperfusion injury

Fig. 7Fig. 7Fig. 7

Protein expression of eNOS (A), iNOS (B), and VEGF (C) by immunocytochemistry in renal ischemia/reperfusion (I/R) mice. The charts show the protein expressions based on the intensity of the brown stained area in different groups with × 400 magnifications. Results were analyzed by Image J software. Data were represented as mean ± SD (n = 5). *P < 0.05 versus the control group (M), **P < 0.01 versus the control group (M), ***P < 0.001 versus the control group (M), ****P < 0.0001 versus the control group (M), $P < 0.05 versus the control group (Norm), $$$P < 0.001 versus the control group (Norm), $$$$P < 0.0001 versus the control group (Norm). Control (normal mice, Norm), Control (Ischemia/reperfusion group which received normal saline, M), I/R + 15 µM SNAP (SM), I/R + 15 µM SNAP-loaded Fmoc-FF + 30%Fmoc-RGD (SHM), I/R + 1 × 106 WJ-MSCs (CM), I/R + 1 × 106 WJ-MSCs + 15 µM Fmoc-FF + 30%Fmoc-RGD (CHM), I/R + 1 × 106 WJ-MSCs + 15 µM SNAP (SCM), I/R + 1 × 106 WJ-MSCs + 15 µM Fmoc-FF + 30%Fmoc-RGD-SNAP (SCHM)

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Stem Cell Research & Therapy

ISSN: 1757-6512