Fig. 3
Nondiabetic plasma-treated SVFs decrease CCL2 and DPP4, and increase IL-10 mRNA expressions in the ATMs of Leprdb/db mice. Leprdb/db SVFs were treated with Lepr+/+ or Leprdb/db plasma and then injected into the inguinal WAT of Leprdb/db mice. Lepr+/+ and Lepr.db/db mice were also treated with PBS as controls. One week later, ATMs and NATMs were isolated from the adipose tissue using microbeads and then subjected to Q-PCR analysis for IL-10 (A), CCL2 (B), and DPP4 (C) mRNA expression. N = 5/group. *p < 0.05, **p < 0.01