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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: miR-126-3p containing exosomes derived from human umbilical cord mesenchymal stem cells promote angiogenesis and attenuate ovarian granulosa cell apoptosis in a preclinical rat model of premature ovarian failure

Fig. 4

PI3K/AKT/mTOR signaling pathway involved miR-126-3p/PIK3R2 mediated OGC proliferation and apoptosis of OGCs in vitro A. Analysis of the ratio of the percentages of apoptotic OGCs in each group. B. Analysis of the ratio of the percentages of proliferative OGCs in each group. C. Representative western blots of PI3K/AKT/mTOR signaling pathway related proteins expression in OGCs in the different treatment group. D. The protein levels of PIK3R2 in OGCs in the different treatment group. E. The protein levels of PI3K in OGCs in the different treatment group. F. The protein levels of p-AKT in OGCs in the different treatment group. G. The protein levels of p-mTOR in OGCs in the different treatment group. H. Analysis of the ratio of the percentages of apoptotic OGCs in each group. I. Analysis of the ratio of the percentages of proliferative OGCs in each group. *P < 0.05 for all figures

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