Skip to main content
Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: miR-126-3p containing exosomes derived from human umbilical cord mesenchymal stem cells promote angiogenesis and attenuate ovarian granulosa cell apoptosis in a preclinical rat model of premature ovarian failure

Fig. 5

miR-126-3p-hucMSCs-exosomes treatment improved ovarian function in POF rat. The average values of body weight, FSH, AMH and E2 were record at the time before the cisplatin treatment and 0th, 1st, 2nd, 3rd and 4th week after exosomes treatment. A. Body weight in each group before the cisplatin treatment. B.FSH levels in each group before the cisplatin treatment. C. AMH levels in each group before the cisplatin treatment. D. E2 levels in each group before the cisplatin treatment. E. Body weight in each group during the experimental period. F. FSH levels in each group during the experimental period. G. AMH levels in each group during the experimental period. H. E2 levels in each group during the experimental period. Comparison of the body weight, FSH, AMH, and E2 levels between groups (POF vs. Normal, POF vs. hucMSCs-exosomes, hucMSCs-exosomes vs. NC-hucMSCs-exosomes, hucMSCs-exosomes vs. miR-126-3p-hucMSCs -exosomes, POF vs. miR-126-3p-hucMSCs-exosomes) at different times. The “ns” (P > 0.05) indicates no statistically significant difference. *P < 0.05, **P < 0.01, ***P < 0.001 for all figures. n = 10 for each group

Back to article page